Antacids reduce the bioavailability of ACE inhibitors. Glucocorticoids, nonsteroidal anti-inflammatory drugs reduce the severity of the hypotensive effect (fluid retention and electrolyte).Potassium-sparing diuretics (spironolactone, triamterene, amiloride), potassium supplements increase the risk of hyperkalemia. Not trenbolone enanthaterecommended simultaneous application of drugs that may cause hyperkalemia, and ACE inhibitors, except in cases of severe hypokalemia (potassium control serum).
In an application with drugs lithium may slow its elimination from the body (requires regular monitoring of blood lithium).
Diuretics, drugs for general anesthesia and muscle relaxants, ethanol increases the risk of excessive blood pressure lowering. The risk of symptomatic hypotension may be reduced by stopping the diuretic a few days prior to treatment with perindopril.
Myelotoxic drugs – increased myelotoxic action.
Risk of arterial hypotension and / or renal failure while taking the drug increased in a significant loss of sodium and water (strict salt-free diet, and / or diuretics, diarrhea, vomiting) or renal artery stenosis (blockage in these situations, the renin-angiotensin system It may result, especially when the first and taking the drug during the first 2 weeks of treatment, a sudden reduction of blood pressure, and chronic renal failure). Before and during therapy is recommended to determine the concentration of creatinine, urea and electrolytes (for 1 month).
In patients with hypertension already receiving diuretic therapy, you should stop taking them (up to 3 days before the appointment of perindopril) and, if necessary, further adding to the treatment again.
Patients with chronic heart failure receiving diuretic therapy, if possible, their dosage must also be reduced for several days prior to administration.
In patients at risk, trenbolone enanthate especially with chronic heart failure decompensation stage, elderly patients and patients with initially low blood pressure, renal impairment or receiving high doses of diuretics, the beginning of the drug should be administered under the supervision of medical staff.
In patients on hemodialysis, should avoid using polyacrylonitrile membranes (development of anaphylactoid reactions). You must stop taking before the upcoming surgery for 12 hours and prevent an anesthesiologist about taking the drug.
Effects on ability to drive a car and perform work requiring special attention
because of the risk of arterial hypotension and dizziness, ACE inhibitors should be used with caution in persons to drive vehicles and engaged in activities that require trenbolone enanthate increased attention and quick motor response. eminence labs